Not at all. For starters,
s/(?:#.*)|\n|\s//g
is the same as
s/#.*|\s//g
Secondly, spaces are allowed in the pattern, so your change is unwarranted.
Finally, comments are allowed in the pattern, so you don't need the substitution at all.
In reply to Re^4: Unpack Many Fields
by ikegami
in thread Unpack Many Fields
by shoness
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