Something like this? 
#!/usr/bin/perl

use warnings;
use strict;

my %hash;

while(defined(my $line = <>)){
  if($line =~ /A:([0-9]+) +B:([0-9]+) +C:([0-9]+) +D:([0-9]+) +CNT:([0
+-9]+) +STR:([0-9]+) +END:([0-9]+)/){
    my($a,$b,$c,$d,$cnt,$str,$end) = ($1,$2,$3,$4,$5,$6,$7);

    my $key = "a:$a,d:$d";
    if(exists $hash{$key}){

      # B and C will be reported if multiple
      my $current = $hash{$key};
      if($current->{b} ne $b){
        $current->{b} = 'MULTIPLE';
      }
      if($current->{c} ne $c){
        $current->{c} = 'MULTIPLE';
      }

      # STR is start, we need the least
      if($str < $current->{str}){
        $current->{str} = $str;
      }

      # END is end, we need the greatest
      if($end > $current->{end}){
        $current->{end} = $end;
      }

      # add to count
      $current->{cnt} += $cnt;

    }else{ # new key
      $hash{$key}{b} = $b;
      $hash{$key}{c} = $c;
      $hash{$key}{str} = $str;
      $hash{$key}{end} = $end;
      $hash{$key}{cnt} = $cnt;
    }
  }
}

# print the results
foreach my $key (keys %hash){
  $key =~ /a:(.*),d:(.*)/;
  my $current = $hash{$key};
  my ($a,$d) = ($1,$2);
  print "A:$a  ";
  print "B:$current->{b}  ";
  print "C:$current->{c}  ";
  print "D:$d  ";
  print "CNT:$current->{cnt}  ";
  print "STR:$current->{str}  ";
  print "END:$current->{end}\n";
}

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In reply to Re^3: working with files by choroba
in thread working with files by smanicka

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