Yes, I did try it without, and in fact the from and reply to work just fine.(with or without) It's more an issue of the "Return-Path". I'm not totally familiar with how the junk mail filters work, but I suspect that some systems compare the domain in the Return-Path with the domain in the From or Reply-To fields in making a determination as to whether or not something is "junk". Thus, from my hosted server, lets say "jupiter.net", mail from my domain my ends up configured as: 
Return-Path: baseuser@jupiter.net
Reply-To: me@mydomain.com
From: me@mydomain.com
To: you@yourdomain.com

[download]

That said, for some reason this doesn't appear to be the case with all receiving domains. For example, when I send mail from me@mydomain.com to me@seconddomain.com hosted by a different company on a different server, the Return-Path appears as I instruct MIME::Lite to display it. (and vice-versa). However, when I send it to me@pacbell.net or me@aol.com, I can veiw the code and see the the Return-Path is "reverted" back to "baseuser@jupiter.net".
--
Filmo the Klown

In reply to Re: Re: Configuring Return-Path with MIME:Lite by filmo
in thread Configuring Return-Path with MIME:Lite by filmo

Title:
Use:  <p> text here (a paragraph) </p>
and:  <code> code here </code>
to format your post, it's "PerlMonks-approved HTML":


  • Posts are HTML formatted. Put <p> </p> tags around your paragraphs. Put <code> </code> tags around your code and data!
  • Titles consisting of a single word are discouraged, and in most cases are disallowed outright.
  • Read Where should I post X? if you're not absolutely sure you're posting in the right place.
  • Please read these before you post! —
  • Posts may use any of the Perl Monks Approved HTML tags:
    a, abbr, b, big, blockquote, br, caption, center, col, colgroup, dd, del, details, div, dl, dt, em, font, h1, h2, h3, h4, h5, h6, hr, i, ins, li, ol, p, pre, readmore, small, span, spoiler, strike, strong, sub, summary, sup, table, tbody, td, tfoot, th, thead, tr, tt, u, ul, wbr
  • You may need to use entities for some characters, as follows. (Exception: Within code tags, you can put the characters literally.)
            For:     Use:
    & &amp;
    < &lt;
    > &gt;
    [ &#91;
    ] &#93;
  • Link using PerlMonks shortcuts! What shortcuts can I use for linking?
  • See Writeup Formatting Tips and other pages linked from there for more info.