I'd be willing to bet that there's a problem with the Perl configuration. From what I've found googling, it appears that Perl should be configured sh Configure -Duseshrplib. Here are the relevant articles:

Re: Build Failure on Perl 5.12 RC3

Re: Build Failure on Perl 5.12 RC3 patch.

In reply to Re: perl5.10.1 doesn't play well with mod_perl2 2.0.4 (or even beta) on OSX by Khen1950fx
in thread perl5.10.1 doesn't play well with mod_perl2 2.0.4 (or even beta) on OSX by merlyn

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