As far as I know, in order for PerlApp to work smoothly you need to have ActivePerl installed in your system and use its repositories to install extra modules.

Assuming you're OK with the above, I suppose it should all work out for you if you create a file argfile.args containing the following lines (which are good for ActivePerl 5.10):

--bind mingwm10.dll[file=C:/Perl/site/lib/Alien/wxWidgets/msw_2_8_9_un
+i_mslu_gcc_3_4/lib/mingwm10.dll,extract,mode=444]
--bind wxbase28u_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWidgets/
+msw_2_8_9_uni_mslu_gcc_3_4/lib/wxbase28u_gcc_wxperl.dll,extract,mode=
+444]
--bind wxbase28u_net_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWidg
+ets/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxbase28u_net_gcc_wxperl.dll,extra
+ct,mode=444]
--bind wxbase28u_xml_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWidg
+ets/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxbase28u_xml_gcc_wxperl.dll,extra
+ct,mode=444]
--bind wxmsw28u_adv_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWidge
+ts/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxmsw28u_adv_gcc_wxperl.dll,extract
+,mode=444]
--bind wxmsw28u_aui_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWidge
+ts/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxmsw28u_aui_gcc_wxperl.dll,extract
+,mode=444]
--bind wxmsw28u_core_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWidg
+ets/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxmsw28u_core_gcc_wxperl.dll,extra
+ct,mode=444]
--bind wxmsw28u_gl_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWidget
+s/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxmsw28u_gl_gcc_wxperl.dll,extract,m
+ode=444]
--bind wxmsw28u_html_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWidg
+ets/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxmsw28u_html_gcc_wxperl.dll,extra
+ct,mode=444]
--bind wxmsw28u_media_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWid
+gets/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxmsw28u_media_gcc_wxperl.dll,ext
+ract,mode=444]
--bind wxmsw28u_qa_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWidget
+s/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxmsw28u_qa_gcc_wxperl.dll,extract,m
+ode=444]
--bind wxmsw28u_richtext_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wx
+Widgets/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxmsw28u_richtext_gcc_wxperl.d
+ll,extract,mode=444]
--bind wxmsw28u_stc_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWidge
+ts/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxmsw28u_stc_gcc_wxperl.dll,extract
+,mode=444]
--bind wxmsw28u_xrc_gcc_wxperl.dll[file=C:/Perl/site/lib/Alien/wxWidge
+ts/msw_2_8_9_uni_mslu_gcc_3_4/lib/wxmsw28u_xrc_gcc_wxperl.dll,extract
+,mode=444]
--bind gdilib/gdiplus.dll[file=C:/Perl/site/lib/Alien/wxWidgets/msw_2_
+8_9_uni_mslu_gcc_3_4/os/gdiplus.dl_,mode=444]
[download]

Argfile.args should be placed in the same folder with the .pl file you have been trying to compile.

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