I found a work-around, just use a different array to index the string array instead of using numbers: 
my @mystrings = ("string") x 200;
my @i = 0..$#mystrings;

m/$mystrings[$i[100]]/;

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Thanks for your help. Should I report this issue?

In reply to Re^2: Match operator fails for elements 100 and higher by thrasher
in thread Match operator fails for elements 100 and higher by thrasher

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