Can you tell us which operating system and version of Perl and IO::Compress are in use here? How are you trying to install this module? An open bug has been raised on this topic. This discussion (in the thread you link to) suggesting use of INSTALL_BASE rather than PREFIX when installing may be of interest, depending on the answers to my previous questions.

Update: edited last sentence

In reply to Re: IO-Compress install failed by marto
in thread IO-Compress install failed by saji

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