You could try 
WriteMakefile( 'DEFINE' => '-DDEBUG',

[download]
But it isn't recommended by compiler/os makers.

You need to compile a debug version of perl and any library your XS links

In reply to Re: How to build DEBUG version of a perl module using Makefile.PL? by Anonymous Monk
in thread How to build DEBUG version of a perl module using Makefile.PL? by vkon

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