Here is a more flexible version that can remove paths or add paths to the beginning or end of the path (note: if you add to the beginning, they will be added in reverse order):

sub import {
  return if $ENV{FIXINIT_PM};
  my $class = shift;
  my @chk = $^C ? '-c' : ();
  $ENV{FIXINIT_PM} = 1;
  my @path = split /:/, $ENV{LD_LIBRARY_PATH};
  while ( my $dir = shift @_ ) {
    last if $dir eq "--";
    if ( $dir =~ s/^-// ) {
      if ($dir eq 'all') {
        @path = ();
        next;
      }
      @path = grep $_ ne $dir, @path;
      next;
    }
    if ( $dir =~ s/^\+// ) {
      unshift @path, $dir;
      next;
    }
    push @path, $dir;
  }
  $ENV{LD_LIBRARY_PATH} = join ":", @path;
  my %env = @_;
  $ENV{keys %env} = values %env;
  exec $^X => @chk, $0, @ARGV;
  die "Could not exec $^X $0: $!";
}
[download]

New pod:

=head1 SYNOPSIS

  # Use before all other use statements
  # Unset LD_LIBRARY_PATH
  use FixInit;

  # Add paths to end of LD_LIBRARY_PATH and set some variables
  # "--" divides paths and env variables
  use FixInit qw(libpath1 libpath2 -- env1 value1 env2 value2);

  # Add paths to beginning of LD_LIBRARY_PATH
  # (Will get added in reverse order)
  use FixInit qw(+libpath2 +libpath1);

  # Remove paths from LD_LIBRARY_PATH
  use FixInit qw(-libpath1 -libpath2);
[download]

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