While it isn't a very elegant solution, the recommend approach is to either die in the Makefile.PL or Build.PL (or BAIL_OUT in a test file) with one of the following messages:
CPAN Testers tools will look for one of those phrases and will send an NA (Not Available) report for that platform.
In reply to Re^4: CPAN Smoke Tests: Some platforms are meant to be broken
by Anonymous Monk
in thread CPAN Smoke Tests: Some platforms are meant to be broken
by saintmike
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