At $15 why are you asking a non-Perl question here instead of TITS (Trying It To See)? There are so many variables with RS-232 because of the huge number of ways that it has been abused over time, it is next to impossible to give a useful answer in any case without know pretty much everything about your hardware and applications, and even then the only way to know for sure is TITS.

True laziness is hard work

In reply to Re: Win32::SerialPort v. New computers by GrandFather
in thread Win32::SerialPort v. New computers by hennesse

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