#! usr/bin/perl -w 
open(FILE,"<gene.txt");
my @lines=<FILE>;
close(FILE);
foreach my $line(@lines)
{
 if($line=~/:/)
 {
  print "$`\n";
 }
}
[download]

output

BRCA1
TNF
OMG
[download]

PS: $` is a special variable used to extract data before the regular expression

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