Think about when you need to remove zeros, then write a regex that does that. Be warned, it's trickier than you think and needs somewhat beyond basic level regex knowledge.

The requirements come down to remove all leading 0 digits except where there is no following digit. Consider:

use strict;
use warnings;

while (<DATA>) {
    s/(?<!\d)0+(?=\d)//g;
    print;
}


__DATA__
010.231.000.049,41145,010.231.000.049,1363,CDU01V43
010.231.000.050,20,010.116.223.024,2803,ZVC629
[download]

Prints:

10.231.0.49,41145,10.231.0.49,1363,CDU1V43
10.231.0.50,20,10.116.223.24,2803,ZVC629
[download]

The (? bits are look back and look ahead anchors. See the perlre documentation for more info on what they do (look for "Look-Around Assertions").

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