Its not clear how you will receive the file or parse it but once you have managed that task you can use a hashref for look-up to retrieve values in a table. The only caveat being that the header lookup must be built individually for each file.

#! C:/Perl/bin/perl
use strict;
use warnings;

my $file_ref =[
    [ 'Non-Syn', 'Splice', 'dbSNP', 'N (Var Depth)', 'N Total Depth', 
+'N Freq', 'T (Var Depth)',  ],
    [ qw( 1    0    0    0    34    0    11 )],
    [ qw( 1    0    0    0    54    0    14 )],
    [ qw( 1    0    0    0    42    0    11 )],
];
my $header_hash_ref = _load_header( $file_ref->[0] );
my $line    = 3;
my $header  = 'N Total Depth';

print "Line -$line- '$header' value is:" .
    $file_ref->[$line]->[$header_hash_ref->{$header}] .
    "\n";

sub _load_header{
    my ( $header_ref ) = @_;
    my ( $return, $x ) = ( {}, 0 );
    for my $header ( @$header_ref ){
        $return->{$header} = $x++;
    }
    return $return;
}

[download]

Provides the output 

Line -3- 'N Total Depth' value is:42

[download]

In reply to Re: Shortcut to identify column numbers in a data file based on header by jandrew
in thread Shortcut to identify column numbers in a data file based on header by ZWcarp

Title:
Use:  <p> text here (a paragraph) </p>
and:  <code> code here </code>
to format your post, it's "PerlMonks-approved HTML":


  • Posts are HTML formatted. Put <p> </p> tags around your paragraphs. Put <code> </code> tags around your code and data!
  • Titles consisting of a single word are discouraged, and in most cases are disallowed outright.
  • Read Where should I post X? if you're not absolutely sure you're posting in the right place.
  • Please read these before you post! —
  • Posts may use any of the Perl Monks Approved HTML tags:
    a, abbr, b, big, blockquote, br, caption, center, col, colgroup, dd, del, details, div, dl, dt, em, font, h1, h2, h3, h4, h5, h6, hr, i, ins, li, ol, p, pre, readmore, small, span, spoiler, strike, strong, sub, summary, sup, table, tbody, td, tfoot, th, thead, tr, tt, u, ul, wbr
  • You may need to use entities for some characters, as follows. (Exception: Within code tags, you can put the characters literally.)
            For:     Use:
    & &amp;
    < &lt;
    > &gt;
    [ &#91;
    ] &#93;
  • Link using PerlMonks shortcuts! What shortcuts can I use for linking?
  • See Writeup Formatting Tips and other pages linked from there for more info.