Hiya, Thank you so much for your help, I tried to run your code just to see how it works. One thing I noticed when I look at the output is that the first column doesn't seem to get transformed. Some duplicates also seem to have been missed.

Like so:

1 Brahui A C/C A/A A/G T/T

100 Hazara A C G A T C C

100 Hazara G C A A T C T

102 Hazara A C/C G/G A/G

In reply to Re^2: How to match duplicate lines in a text file and extract only one of those lines to a new file by danica
in thread How to match duplicate lines in a text file and extract only one of those lines to a new file by danica

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