After reinstalling as directed above, check to make sure that in the IIS configuration for .pl files that the executable path is something like 
C:\Perl\bin\Perl.exe %s %s  <-- important to have these two switches

In reply to Re: Cannot run Perl under IIS (Win2000 pro) by earthboundmisfit
in thread Cannot run Perl under IIS (Win2000 pro) by Pingu

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