Use a stored procedure like this maybe, 
my $create_proc_upd = <<'eof'; 
CREATE PROCEDURE upd() 
BEGIN

 SET @tid:=(SELECT Team_ID FROM Teams WHERE Name='Thunder');
 UPDATE Games SET Away_Team_ID=@tid WHERE Date='2012-05-29';
             
 SET @tid:=(SELECT Team_ID FROM Teams WHERE Name='Spurs');
 UPDATE Games SET Home_Team_ID=@tid WHERE Date='2012-05-29'
 
 END            
eof
            
$dbh->do('DROP PROCEDURE IF EXISTS upd');
$dbh->do($create_proc_upd);
$dbh->do('CALL upd');

[download]
poj

In reply to Re: Followup on executing multiple mysql commands in one call by poj
in thread Followup on executing multiple mysql commands in one call by membender

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