I highly suggest you pick up a copy of Jeff Friedl's "Mastering Regular Expressions", where this example is discussed in great length. The Final answer is:

s{(?:"(?:\\.|[^"\\])*")|(?:/\*[^*]*\*+(?:[^/*][^*]*\*+)*/)}{}g
[download]

Which nicely "unrolls the loop" for double-quote-aware comment removal. Pretty slick, huh? Check the book out ASAP!