I've never used Profiler, but after a quick squint at the docs one possible way forward would be to use the bad_pkgs option to stop it from profiling everything except your main line code. If that is successful, then you could remove packages from the option until you break it again. Once you know which package(s) are causing problems, then you could try using the bad_subs option to exclude stuff in the bad package and then put them back until you break again.

It might be a rather tedious process, but you might find that you don't need to be profiling much below your main-line code anyway.