On bugtraq, there was an announcement concerning Safe.pm 2.0.7 and earlier with Perl 5.8.0 and earlier. From the email:
1. Problem Description Safe.pm 2.0.7 and earlier, when used in Perl 5.8.0 and earlier, may allow attackers to break out of safe compartments in (1) Safe::reval or (2) Safe::rdo using a redefined @_ variable, which is not reset between successive calls. The Common Vulnerabilities and Exposures project (cve.mitre.org) has assigned the name CAN-2002-1323 to this issue.

Refer to http://cve.mitre.org/cgi-bin/cvename.cgi?name=CAN-2002-1323 for more info.

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Re: Some versions of Safe considered unSafe
by ysth (Canon) on Apr 04, 2004 at 13:43 UTC
    Wow, they move a little slowly, that seems to have been in "candidate for the CVE list" status for a year now.

    Note that perl5.6.2 includes the fixed Safe 2.10. (Not sure where they got the 2.0.7 notation from, Safe was at version 2.07 in 5.8.0 and 2.10 in 5.8.1.)