Depending on what type of applications you code, you might want to look at Maypole from Simon Cozens. He's posted a couple of articles at http://www.perl.org/ and also has a website dedicated to Maypole at http://maypole.simon-cozens.org/. Please note that this code is still in a state of flux.

There has also been a couple of discussions about Maypole on Perl Monks. See Maypole on perl.com and Building Enterprise Web Applications with Maypole.