I don't know how to implement a solution to your question (Maybe something under the Win32:: module set?), but if you want to know this because of a window constantly popping up, download either Spybot: Search and destroy or Adaware, then update and run them. If you just want to know how to make a script click something, I suggest you rephrase your question to specifically say what it is for if you had something in mind, not to deal with a spyware problem (which is what your last post regarded). If you "just want to know" (like myself on several occasions) state that it is because you are just curious.

Hope this helped

P.S. If you want to open programs with Perl, check out the system and exec functions.

UPDATE: I am giving you the benefit of the doubt regarding this by assuming you are not freak. If this is for some sort of popup scoring thing, forget getting any help from me