I think it's a matter of taste. It may look cleaner in a cascaded dereference construct, but I tend to avoid it as much as I can for religious reasons (it looks OOPish ;) )

You can pass arguments with the ampersand syntax too: &$command ($arg1, $arg2);

Update: There are issuse with a bare & call and @_, see code:

$ perl
sub foo {
  my $x = sub {print "@_"};
  &{$x};
}

foo qw/bar baz/;
^D
bar baz
[download]

If you don't want to transfer @_ use &{$x} (); (or $x->();)