If you can guarantee that you will only ever be using Internet Explorer, take a look at the ActiveX extension called PerlScript that ActiveState has released. (If you download ActivePerl, you automatically get it.) The documentation is very spotty, but you can do some really neat things.

Note - this will require that anyone using your website must have ActivePerl installed. But, if you do so, you can actually replace all your JavaScript with PerlScript.

Note further - PerlScript is not a complete version of Perl. There are some edge cases and dark corners you may not be able to do. But, you will have all the major capabilities of Perl. (Basically, if you don't know what I'm referring to, don't worry about it. I played with PerlScript on and off for a few months and didn't find much that it couldn't do.)