We have an IBM 825 iSeries (aka an AS/400) where I work.

I regularly access DB2 files on it by using the ODBC driver that comes with iSeries Access (aka Client Access). It's an optional component, so you might to install it... and of course, this is assum taking for granted that your environment is at least a little bit like mine.

I'm running Windows XP and ActiveState. Using DBI and the ODBC driver, I'm able to retrieve the data with normal SQL statements, and it's great!

John