No one can really help you unless you show us what is actually in your .CMD file. This is really just a DOS .BAT file so can contain any valid dos shell syntax. It is not immediately apparent why you should need to do this. More details please.

my $file = 'c:/file.cmd';
open F, $file or die "Can't read $file, perl says $!\n";
while(my $line = <F>){
    # parse the line to get data
}
close F;
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