seek FILE,0, 2;  #go to EOF 
seek FILE,-2048,2; #get last 2k bytes
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Not much point in seeking twice is there? The latter seek, seeks to 2048 bytes from the end - no reason to first seek to the end. And for readability (and portability) reasons, I would use seek FILE, -2048, SEEK_END;, importing the constant from Fcntl.