I think what you're asking is, can a script run from inside a virtual directory and access material from outside the virtual directory? The answer is yes - but only if that material has the proper permissions settings. You can't modify system files, for instance.
Comment on Re: work outside of a virtual directory
Yes, I mean this. I need well thought script which will copy and deliver me by email some files that located outside this virtual directory. I will set file type or file name via script GUI. I'll wondering if someone can help me.