Another alternative is to use Tie::File. This lets you treat a file as a regular array variable. This is very convenient because it is easy to understand what is going on, as long as you are familiar with perl arrays.

use Tie::File;

my( $file_name, $arg1, $arg2 ) = @ARGV;

# open the file with tie
tie my @file_lines, 'Tie::File', $file_name or die;

# delete the first line
shift @file_lines;

# filter out lines containing 'sandwich'
@file_lines = grep !/^$arg1,$arg2,/, @file_lines;

# close the file with untie.
# IMPORTANT: always untie when you are done!
untie @file_lines or die "$!";
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Update: Note that perl does not actually load the file into the array. It only appears to do so.