Use Perl's grep!
@array = grep { index($_, 'certain case-sensitive string') == -1 } @array;
or
@array = grep { index(lc($_), lc('certain case-insensitive string')) == -1 } @array;
or
@array = grep { !/certain regexp/ } @array;

As ikegami says, you should use grep. He gives a good example for excluding elements based on a regular expression, but you might also want to exclude elements based on string equality (which would be far faster, though a different algorithm would probably be even better):

  my @new = grep { $_ ne "certain string" } @old;
[download]

Or, perhaps you want to search for a substring:

  my @new = grep { index($_, "certain string") == -1 } @old;
[download]

Just trying to give you some more ideas of how you can use grep... HTH

Update: no fair! ikegami updated his post in the time while I was posting this. Cheater. :-)

Remove elements that do not match the RegEx /B.*?y/

use strict;
use warnings;
my  @aTemp = qw(Fred Betty Barney Wilma);
@aTemp = grep{$_ =~ /B.*?y/} @aTemp;
print join',',@aTemp;
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Remove elements that *do* match the RegEx /B.*?y/

use strict;
use warnings;
my  @aTemp = qw(Fred Betty Barney Wilma);
@aTemp = grep{$_ !~ /B.*?y/} @aTemp;
print join',',@aTemp;
[download]

Note: The other examples in this thread that use 'index' are more preferable for what you asked ... but this is an alternate way in case you are curious.

Moreover, you might want to check out Categorized Questions and Answers where you can find fast answers to basic questions like How do I completely remove an element from an array ... categorized Q&A is very useful.

how's that? --bibo UPDATE: no that's really wrong. ignore....

That doesn't remove any elements, it just undefines an element. (splice(@foo, $i, 1) removes element $i.) Also, you didn't address finding the elements that don't "contain a certain string".