Each templating system / text pre-processor, or whatever is intended for a particular audience. You have to analyze what functionality you're going to need, and who is going to be using it.

If you can take care of 99% of your site with a CMS system that requires no technical, and leave the last 1% to someone with some programming skills, it's probably better than giving them something they can accidentally break.

For instance, back in my undergrad days, the group I worked for did a web page that called an SSI for the bulk of its content. Unfortunately, the site's 'owner' kept editing the page in a WYSIWIG editor which pulled down its content through HTTP ... I tried leaving a hint, but as they never looked at the source, they never found my not-so-subtle hint.

My advise, if you're going to be the only one using it, is to take a look at the syntax, and see if it makes sense to you. If it does, then you're probably fine -- but if the maintainer has a different mindset than you do, you might want to look at something else.

If whoever is developing content has absolutely no programming skills at all, and you're not dealing with database backends and the like, you might also take a look at Markdown.