Maybe this isn't a code issue, but more of a permissions issue. If your web server doesn't have appropriate permissions to your file, then it can't access it to do what you want. The only other thing I can see (and I have limited ASP experience) is that when I've used cmd.exe /c in other perl scripts, I had to quote the command.

cmd.exe /c "C:\\perl\\bin\\perl PATH_TO_MY_SCRIPT\\SCRIPT.PL ARGS".</p
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Hope this helps