in reply to OT - Sending Email on Windows

Yes Blat does need to know the address of an SMTP server to work.

Your best best is to get the local IIS to act as an SMTP relay - the error you are getting is simply an indication of its unwillingness to relay as you have got the configuration incorrect. I am assuming here that you are using Windows 2000 and you have an administrative account (the instructions are similar for XP).

The default configuration of the SMTP service on Windows 2000 SP2 and better is not to relay at all so you are going to have to allow connections and relaying from the localhost only:

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Re^2: OT - Sending Email on Windows
by jhourcle (Prior) on Apr 22, 2005 at 11:25 UTC

    And for those who aren't familiar with localhost -- you'll have to specifically connect to the loopback address for this to work. If your outgoing IP address is 10.0.0.1, you'd not be able to pass mail if you connect to that e-mail address.

    You would need to set your SMTP server in whatever other program to 127.0.0.1