Hi,

To avoid confusion, you could have Stated the operating system in the question/question title :D
Regrdless, using DBD::ODBC in conjunction with MDB tools should be a place to start looing.
MDB tools: provides "A sparse but functional ODBC driver is included as well" as stacks of other stuff.

However, (shameless 'I hate MS Access use MySQL if you can' rant) if moving from MS Access to MySql is an option, you may want to have a look at this node "Re: Converting Microsoft Access to Perl/Tk/DBI" where I detail a tool developed for (almost) painless migration from Access to MySQL.

Hope this helps.

Martin