See my comment below. There probably is a way to get this to work, but I think it would be easier if you move to apache: especially because there are more people willing to help you on forums and that sort of thing.

The most "plug and play" solutions I know with web-perl for beginners usually involve apache, and this includes on windows (which is my setup). Apachefriends is pretty easy to setup.

If there is an "easy" way to get perl to play nicely with IIS I would be interested in learning about this as well.

Update: perl on iis is definitely doable, but I stand by my judgement that ultimately this will be easier if you switch to apache.