Joel Spolsky once wrote on this topic:

When you go too far up, abstraction-wise, you run out of oxygen. Sometimes smart thinkers just don't know when to stop, and they create these absurd, all-encompassing, high-level pictures of the universe that are all good and fine, but don't actually mean anything at all.

http://www.joelonsoftware.com/articles/fog0000000018.html