What exactly do you want to match?
This line in a big file? some words out of it?
please read how (not) to ask a question if you want help.

#!/usr/bin/perl
use Data::Dumper;
use strict;

my $ln = "HOST_RESOURCE_MONITOR rtbd:service=ResourceMonitorService,na
+me=ResourceMonitor,type=HOST true Started 1 day, 12 hours, 2 minutes,
+ 30 seconds and 476 milliseconds";


if ($ln =~ m/^HOST.*?seconds$/ ) {
print "ok";
}
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