I guess this related to another post of yours Executing system command?

(Referring to the other post)

First of I would recommend that you update one post so that people can understand the whole picture instead of juggling between posts

Next, providing more detailed description on what you have tried will be helpful. We understand your mailing list is not triggering your perl script but works from command line. But we will not have any clue as to why certain things are happening on your system unless we see error messages from your script directly. . It is hard to decide whether it is your mailing list app or perl scrip that is causing the problem here

-SK