This is not a Perl question.

That aside, try removing the "ismap" statement from your <img ...> tag. It may be forcing your client to assume the map is a server-side (instead of client-side) one.

e.g.

<img SRC="/cgi-bin/webpage/simpleImage.cgi?seq1=humPrPDpl&seq2=mouPrPD
+pl&tissue=all" USEMAP="#image" BORDER="0">
[download]