Regardless of what method you use, you will require a program or demon running on the windows box to recieve or notice the data, and run the windows program. You could use a rsh shell or a SOAP daemon or a program that monitors a directory, but something has to be there waiting.

And since you also have yet to write the script that interfaces with the COM object, why not combine the two and have the script open a port, wait for the inbound data, process it through the COM object and then return the response. Either Perl or Python are fine for that.