Sure, grep will simplify that, with a minor change in behavior - maybe for the better.

sub lsearch {
    my $item = shift;
    grep { $item eq $_[$_] } 0 .. $#_;
}
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That will return the empty list for false, and otherwise a list of each index that succeeds

Usage becomes, for your example,

for (reverse lsearch $item, @list) {
    splice @list, $_, 1
}
# or
splice @list, $_, 1 for reverse lsearch $item, @list;
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so all instances of $item are removed from the array. The reverse call is needed to preserve the indexes from being shifted out of sync by splice.

An alternative is to define a winnow() function to do it all:

sub winnow {
    my $item = shift;
    grep { not $item eq $_ } @_;
}

@list = winnow $item, @list;
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That is maybe less flexible, but I think cleaner.