IF you already know basic CGI then it is generally just a matter of modifying your webserver configuration to allow perl scripts to be executed based on their extension in all directories or to specifically empower individual scripts.

In apache this is as easy as:

# .pl everywhere!
AddHandler cgi-script .pl
#
# specific script
<Location /index.pl>
  SetHandler cgi-script
</Location>
[download]

A third, rather more involved method is mod_perl. With other webservers, you are on your own...

--
$you = new YOU;
honk() if $you->love(perl)