"knuth abstraction experience more less" turns up an old salon article on Knuth containing the following paragraph...

But programmers ignore "the very pulse of the machine" (a Wordsworth quotation found in Volume 1) at their peril. As Lyle Ramshaw, a former graduate student of Knuth's, points out, "Don claims that one of the skills that you need to be a computer scientist is the ability to work with multiple levels of abstraction simultaneously. When you're working at one level, you try and ignore the details of what's happening at the lower levels. But when you're debugging a computer program and you get some mysterious error message, it could be a failure in any of the levels below you, so you can't afford to be too compartmentalized."

...it's not an exact quote from Knuth, but it seems to afirm that such a sentiment did/does exist.