Let the spammers defeat themselves and use the same tricks they use to escape the anti-spam filters: have a look at
The Spammers' Compendium (Being a public exposition of tricks,
secret ploys, ruses and techniques
employed by those that send many
scurrilous messages through the ether
using the mysteries of electronics and
other modern marvels to dazzle the eye,
lighten the wallet and clog the recipient).
CountZero
"If you have four groups working on a compiler, you'll get a 4-pass compiler." - Conway's Law