Nice node nferraz, special thanks for "paste mode", I'v looked for that. Heres my 2c.:

" run srcipt from Vim pressing F5
map <silent> <F5> :!perl ./%<CR>
[download]

Can't remember where did I get it, I guess its from article at http://mamchenkov.net but its down for now(I hope temporarily). Updated
It is up now, and I'd like recommend it to everyone, cause its nice and useful article as jhourcle has mention above, with good explanation of every option and even illustrated.