There is a module called Filter::Macro which can do this type of thing. If you were to use it, the strict and warnings pragmas could easily be loaded into each of the 50+ files.

There are two downsides, though. The first is that Filter::Macro uses source filtering to accomplish its task. The second is that you'd still have to add one line to each of your 50+ files... the line which "uses" the module which "uses" the Filter::Macro module. From that point on, however, you would be able to simply update that one module where you used Filter::Macro and wouldn't have to touch the 50+ pages again.

Say you wanted to add Carp to your 50+ files, for example. You would just add it to your module which uses Filter::Macro, and it's basically added to all your 50+ files.

I've only used Filter::Macro on my test suite files so far, but it appears to work as advertised.