It seems to me the answers given so far are too complicated because everyone wants to write Perl where they don't need it. You want a shell script instead. Source the environment file to set up the environment, then start the Perl script.

#!/bin/sh

source /etc/profiles/bashrc.ora.v.10
perl program.pl
[download]

And, if your Perl program is already running and the profile file has changed, you can exec the script again, effectively starting fresh.