in reply to Altering data files

If the "seq_name" line is _always_ directly after the "StrCatDone" line, then this (untested) one-liner should do it (not very memory-efficient though):
perl -0777 -pe 's/(?<="StrCatDone" "1";\s+"seq_name" ")sequence.V5_0(? +=";)/sequence_FOO/sg' datafile.txt
Alternatively, you could set $/='}' (see perlvar) and apply that regex to each "line", writing out to another file as you go.