Have you looked at Net::FTP? It seems to me that it is very easy to implement what you want in a few additional lines. Maybe something like the untested following code:

#!/usr/bin/perl -w
use strict;
use Net::FTP;
$|++;

my ($host,$user,$password) = ('ftp.example.com','willdooUK','supers3kr
+3t');

my $ftp = Net::FTP->new($host, Passive => 1, Debug => 1)
    or die "Couldn't connect to '$host': $!";
$ftp->login($user, $password)
    or die "Couldn't login to '$host' as '$user'.";
$ftp->binary; # just to be safe

for my $line (<DATA>) {
    chomp;
    next unless /\S/;
    my ($local, $remote) = split /;/, $file;
    if (! $remote) {
        warn "Invalid remote name for '$local', ignored";
    } elsif (! -f $local) {
        warn "Invalid local filename '$local', ignored";
    } else {
        print "Storing '$local' as '$remote'";
        $ftp->put($local,$remote);
        print ", done.";
    };
};
__DATA__
c:/web/my_local_file.txt;some/remote/dir/target.html
d:/another/web/another_file.html;some/remote/dir/target.css
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