I'm experiencing a problem that seems very close to yours. I am running (rele3ased) Vista 64, and Strawberry Perl Alpha 2.

Compile attempts fail - see snippets below - I'm trying to install Date::Calc. The pre-req Bit::Vector fails ...

cp lib/Bit/Vector/String.pod blib\lib\Bit\Vector\String.pod
cp lib/Bit/Vector/String.pm blib\lib\Bit\Vector\String.pm
gcc -c          -s -O2 -DWIN32 -DHAVE_DES_FCRYPT -DPERL_IMPLICIT_CONTE
+XT -DPERL_IMPLICIT_S
YS -fno-strict-aliasing -DPERL_MSVCRT_READFIX -s -O2      -DVERSION=\"
+6.4\"     -DXS_VERSI
ON=\"6.4\"  "-IC:\strawberry-perl\perl\lib\CORE"   BitVector.c
gcc: installation problem, cannot exec `cc1': No such file or director
+y
dmake.EXE:  Error code 129, while making 'BitVector.o'
  C:\strawberry-perl\dmake\bin\dmake.EXE  -- NOT OK
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Then, Date::Calc compile also fails:

cp Calc.pm blib\lib\Date\Calc.pm
C:\strawberry-perl\perl\bin\perl.exe C:\strawberry-perl\perl\lib\ExtUt
+ils\xsubpp  -typemap
 C:\strawberry-perl\perl\lib\ExtUtils\typemap -typemap typemap  Calc.x
+s > Calc.xsc && C:\s
trawberry-perl\perl\bin\perl.exe -MExtUtils::Command -e mv Calc.xsc Ca
+lc.c
gcc -c          -s -O2 -DWIN32 -DHAVE_DES_FCRYPT -DPERL_IMPLICIT_CONTE
+XT -DPERL_IMPLICIT_S
YS -fno-strict-aliasing -DPERL_MSVCRT_READFIX -s -O2      -DVERSION=\"
+5.4\"     -DXS_VERSI
ON=\"5.4\"  "-IC:\strawberry-perl\perl\lib\CORE"   Calc.c
gcc: installation problem, cannot exec `cc1': No such file or director
+y
dmake.EXE:  Error code 129, while making 'Calc.o'
  C:\strawberry-perl\dmake\bin\dmake.EXE  -- NOT OK
Running make test
...
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I removed Activestate because I could not get PPM (64-bit) to work - was hoping for more luck with Strawberry. Sthis is a one-time install, so my ENV is clean.

Update 1:I made marginal progress on this, by copying cc1.exe from C:\strawberry-perl\mingw\mingw32\bin (which is NOT in the PATH) to C:\strawberry-perl\dmake\bin which IS in the PATH. The process now finds, and runs cc1, but there is a new issue:

It appears that the INCLUDE path C:\strawberry-perl\mingw\include is being ignored - the compile fails because it cannot find a multitude of header (.h) files. Please help - I am not a C programmer.

Writing Makefile for Bit::Vector
Writing patchlevel.h for C:\strawberry-perl\perl\bin\perl.exe (5.00800
+8)
cp lib/Bit/Vector/Overload.pm blib\lib\Bit\Vector\Overload.pm
cp Vector.pm blib\lib\Bit\Vector.pm
cp Vector.pod blib\lib\Bit\Vector.pod
cp lib/Bit/Vector/Overload.pod blib\lib\Bit\Vector\Overload.pod
cp lib/Bit/Vector/String.pod blib\lib\Bit\Vector\String.pod
cp lib/Bit/Vector/String.pm blib\lib\Bit\Vector\String.pm
gcc -c          -s -O2 -DWIN32 -DHAVE_DES_FCRYPT -DPERL_IMPLICIT_CONTE
+XT -DPERL_IMPLICIT_S
YS -fno-strict-aliasing -DPERL_MSVCRT_READFIX -s -O2      -DVERSION=\"
+6.4\"     -DXS_VERSI
ON=\"6.4\"  "-IC:\strawberry-perl\perl\lib\CORE"   BitVector.c
BitVector.c:8:80: stdlib.h: No such file or directory
BitVector.c:9:80: limits.h: No such file or directory
BitVector.c:10:80: string.h: No such file or directory
BitVector.c:11:80: ctype.h: No such file or directory
BitVector.c: In function `BitVector_Error':
BitVector.c:508: error: `NULL' undeclared (first use in this function)
BitVector.c:508: error: (Each undeclared identifier is reported only o
+nce
BitVector.c:508: error: for each function it appears in.)
BitVector.c: In function `BitVector_Boot':
BitVector.c:547: error: `size_t' undeclared (first use in this functio
+n)
BitVector.c:580: error: `NULL' undeclared (first use in this function)
... many more syntax errors because it cannot find .h files ......
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Update 2: SUCCESS!

Finally got Date::Calc and dependents to compile and install after a few more hacks:

copy C:\strawberry-perl\mingw\lib\gcc\mingw32\3.4.5\include C:\strawbe
+rry-perl\perl\lib\CORE

copy /s C:\strawberry-perl\mingw\include C:\strawberry-perl\perl\lib\C
+ORE
set LIBRARY_PATH=C:\strawberry-perl\mingw\lib;C:\strawberry-perl\mingw
+\lib\gcc\mingw32\3.4.5
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Admittedly, these are not good things to do - I'm hoping the Strawberry perl developers will put the right includes in their install process.

I have never posted a per bug report before, and am a little shy on that - is this an appropriate thing to post on their forum ?